The 2021A European Physical Society conference for high energy physics will follow a purely online format. The organisation of the conference is hosted jointly by the University of Hamburg and by the research center DESY. The conference will feature plenary, review and parallel sessions covering all major areas and developments in high energy and particle physics, astroparticle physics, neutrino physics and related areas. Abstract submission for the conference will open on 10 February and close on 7 May 2021. Final timetables of the conference will be published in early June 2021.