Regulatory RNAs are essential for bacteria and archaea to adapt, colonize, and defend. They work seamlessly with RNA machinery and inspire synthetic switch engineering. We can't wait to see you at our conference! Topics include new regulatory mechanisms, RNA-protein networks, microbial pathogenesis, synthetic biology, RNA turnover, bacteriophage evolution, and the CRISPR immune system. This meeting aims to foster collaboration and idea exchange among researchers at all career stages. Oral presentations will be selected from submitted abstracts to cover the latest advances.